PASCAL 2009 Problem 22

In the diagram, PQ and RS are diameters of a circle with radius 4. If PQ and RS are perpendicular, what is the area of the shaded region?

Image

Answer Choices
A. 16+4\pi
B. 8+8\pi
C. 8+4\pi
D. 16+16\pi
E. 16+8\pi